Stem Cells have the remarkable potential to develop into numerous different cell types and serve as the body’s primary internal repair system.
The innate ability of stem cells to differentiate into other types of cells with specialized functions (blood, brain or tissue cells) replenishes and regenerates the body from the effects of age and disease.
Hyperbaric oxygen therapy has been shown to significantly increase the concentration of circulating stem/progenitor cells within the peripheral circulation system. By increasing blood plasma oxygen levels, bone marrow derived stem cells were shown to significantly proliferate and mobilize.
The proposed mechanism of action was through a nitric oxide dependent mechanism. This evidence plays a key role in regenerative medicine as the increased number of stem cells in the body have the ability provide enhanced and accelerated physiological repair.
Enhance stem cell activity:
- Activates nitric oxide synthase type 3 (NOS-3)
- Proliferates and mobilizes bone marrow derived stem cells
- Improves engraftment and differentiation of several prognitor cell types in organs such as the spleen, bone marrow, brain, peripheral nerve, pancreas, cartilage & heart
- Increases colony-forming cells
- Stimulates stromal-derived growth factor
- Reduces high ROS levels
- Promotes endothelial growth factor-2 for angiogenesis
- Increases CD34 expression & pluripotent stem cells
Enhance healing from disease/injury:
- Accelerates growth & repair of damaged tissue
- Improves tissue regeneration & organ functionality
- Promotes neurogenesis
- Stimulates osteogenesis
- Ameliorates diabetic symptoms
- Enhances recovery from heart attack