Chronic Refractory Osteomyelitis is a bacterial infection of the bone marrow. It is difficult to treat due to the scarce amounts of blood vessels in the bone. Consequently antimicrobials do not penetrate bone well. Patients with osteomyelitis in the skull, spine or sternum have a high risk of morbidity and mortality.
- Delivers oxygen in plasma to areas with little or no perfusion.
- Provides 02 to fibroblasts-cells that make connective tissue-promoting healing in hypoxic tissue.
- Enhances the effects of some antibiotics.
- Prevents PMN leukocytes from adhering to to damaged blood vessel linings decreasing inflammation.