Clostridial myositis with myonecrosis or gas gangrene is an acute, rapidly porgressive, nonpyogenic, invasive clostridial infection of the muscles, characterized by profound toxemia, extensive edema, massive death of tissue, and a variable degree of gas production. This type of infection is caused by an anaerobic bacilli.
HBOT is used adjunctively with surgery and antibiotics.
- Tissue p02 >300mmHg stops exotoxin production.
- Compression reduces gas bubble size and tissue pressure improving perfusion.
- Increases in free radical production kills (anaerobic) bacteria.
- Less heroic surgeries are required.
HBO clarifies the demarcation area.