Clostridial myositis with myonecrosis or gas gangrene is an acute, rapidly porgressive, nonpyogenic, invasive clostridial infection of the muscles, characterized by profound toxemia, extensive edema, massive death of tissue, and a variable degree of gas production. This type of infection is caused by an anaerobic bacilli.

HBOT is used adjunctively with surgery and antibiotics.

  • Tissue p02 >300mmHg stops exotoxin production.
  • Compression reduces gas bubble size and tissue pressure improving perfusion.
  • Increases in free radical production kills (anaerobic) bacteria.
  • Less heroic surgeries are required.
    HBO clarifies the demarcation area.